GLP-1 and Incretin Drugs

Off-label use of medications like Ozempic, Wegovy, Mounjaro, and Zepbound is becoming increasingly common to address weight management, insulin resistance, and diabetes related complications in type 1 diabetes. New expert recommendations provide a framework for safe use while large trials are ongoing. 

Choosing a diabetes medication that’s right for you depends on your needs. If an incretin therapy like Mounjaro or Ozempic is what you need to manage your blood sugar and support your overall health, then there’s no reason to delay starting one.

Ozempic (semaglutide) is a GLP-1 medication used for blood sugar management that also provides heart and kidney protection in people with type 2 diabetes. It’s available as a once-weekly injectable, and as of May 2026, a once-daily pill.

For people seeking an oral GLP-1 medication, Foundayo is now available in the U.S.

Insurance issues and side effects are some of the reasons people need to stop taking a GLP-1 drug for diabetes or weight management. Here’s how to navigate the transition and protect your health.

GLP-1 drugs were once met with skepticism, but now their proven health benefits have brought them unprecedented levels of hype. Researchers talked about how we got here and what they hope to see next for these life-changing medications.