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Type 2 Diabetes Clinical Trials

Published: 11/11/22 12:45 pm
By Arvind Sommi

Several trials are studying innovative medications to help people living with type 2 diabetes and its complications, such as chronic kidney disease and diabetic retinopathy. Here are some exciting clinical trials you can join now.

Managing type 2 diabetes can be challenging, but researchers around the world are working to achieve a brighter future. Clinical trials allow researchers to evaluate the safety and efficacy of new drugs and technologies – but these trials would not be possible without volunteer participants such as yourself! Here are several trials specifically aimed at enrolling people with type 2 diabetes:

1. Combination Therapy for Kidney Disease and Type 2 Diabetes

A Bayer clinical trial is seeking to evaluate the safety and efficacy of taking finerenone, used to treat chronic kidney disease, alongside empagliflozin, an SGLT2 inhibitor. This study could pave the way for an innovative combination therapy that is more convenient for people with diabetes.

2. How Does Semaglutide Affect Your Eye Health?

Learn about a clinical trial designed to study the long-term effects of the GLP-1 receptor agonist semaglutide on eye health and how to enroll if you are eligible.

3. Metformin for People with Chronic Kidney Disease

Metformin is the world’s most common diabetes medication and is often referred to as a miracle drug. However, metformin use in those with chronic kidney disease (CKD) has been controversial. This study investigates a new delivery mechanism for metformin that could make it safer for those with CKD.

4. Once-Weekly Basal Insulin Combined With Semaglutide Could Help Lower Glucose Levels

Learn more about how you can participate in a clinical trial from Novo Nordisk testing whether a new once-weekly insulin injection, when combined with semaglutide (also injected once weekly), can help people with type 2 diabetes better manage their glucose levels and lose weight.

More Trials:

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes (SURPASS-EARLY)

  • This study aims to evaluate the safety and efficacy of tirzepatide compared with other existing treatment options in participants with type 2 diabetes.

A Research Study Looking at How Well a Combination of the Medicines Semaglutide and NNC0480-0389 Works in People With Type 2 Diabetes

  • This study will compare changes in A1C as a result of several dosage strengths of a new investigational drug, given with or without semaglutide. The results from this study will help determine doses of the investigational drug to be used in future clinical trials. 

A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE) (REALYSE)

  • This study compares Rybelsus with other medications in people with type 2 diabetes. All medicines used in this study are oral tablets that lower blood glucose levels in people with type 2 diabetes.

Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes (STEP HFpEF DM)

  • This study will evaluate semaglutide against a placebo to measure changes in body weight and heart failure symptoms among people with type 2 diabetes and heart failure.

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About the authors

Arvind Sommi joined the diaTribe Foundation in 2021 after graduating from the University of Florida with a degree in Biology. Sommi is an Editor for diaTribe Learn. Arvind Sommi joined... Read the full bio »